Balls Hen House Pharmacy

Our mission is to empower our patients with the knowledge necessary to make informed decisions regarding their health and optimize the use of their medications through screenings, seminars, and consultations.
We will serve as a knowledgeable and trustworthy source by providing drug and health-related information in a confidential and professional manner.

Volume 5, Issue 8

Zaditor®: A New Over-the-Counter Treatment Option for the Eyes
Contributed by: Jessica Koerner, Pharm.D.
                      Community Pharmacy Resident

February 2007

What is allergic conjunctivitis?
Allergic conjunctivitis is a condition that many people who suffer from allergies frequently experience.  Symptoms include itchy eyes, red eyes, tearing, mucous production, and swelling of the eyelids.  Allergic conjunctivitis can be seasonal or perennial.  The seasonal condition is more common and results from exposure to allergens such as ragweed, pollen, or molds.  The less common perennial condition occurs throughout the year and is usually triggered by allergens such as dust or pet dander.

What are treatments for allergic conjunctivitis?
Treatment of allergic conjunctivitis is based upon the identification and elimination of the allergens causing the reaction.  Because many of the known allergens cannot always be eliminated or avoided, treatment with medications that alter the body's immune response are often used.  Such medications include antihistamines and mast cell stabilizers.  Antihistamines work by blocking the effect of histamine, which causes the symptoms associated with allergies.  Mast cells are responsible for releasing histamine and starting the allergic response; therefore, stabilizing the mast cells will prevent the response.

Until recently, over-the-counter options for the treatment of allergic conjunctivitis were limited to antihistamine-decongestant ophthalmic products containing naphazoline and phenerimine.  Products available include the following: Naphcon-A
®, Opcon-A®, Visine-A OTC®, and others.  Although these products are effective, they are only recommended to be used short-term, which is no more than three days due to risk of side effects associated with long-term use of decongestants. Because most individuals suffer from the symptoms of allergic conjunctivitis for many days, the over-the-

counter products available are not a good treatment option.  On the other hand, mast cell stabilizing medications are ideal for preventing symptoms and are safe for long-term use; however, the main disadvantage to these products has been that they require a prescription. 

Ketotifen (Zaditor®)

Ketotifen (Zaditor®) is the first of its class to be available over-the-counter and is approved for the treatment of itchy eyes due to allergic conjunctivitis. It is an ophthalmic medication containing both an antihistamine and a mast cell stabilizer, which allows it to have both immediate and prophylactic properties.  Zaditor® is safe for both short-term and long-term use.  Administration includes instilling one drop twice daily into both eyes.  Contact lenses should be removed prior to using the product and may be reinserted after ten minutes if eyes are not red.

The availability of Zaditor® without a prescription is likely to benefit many individuals suffering from seasonal or perennial allergic conjunctivitis.   Be sure to ask your physician or pharmacist about Zaditor® if you think it might be an option for you.  Also, for more information about Zaditor® and allergic conjunctivitis you can visit www.zaditor.com (coming soon) or www.
webmd.com.

Co-edited by:
Sarah Hare, Pharm.D.
Miranda Wilhelm, Pharm.D.

Inside this issue:

Next Page