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What is gout?
Gout is a type of arthritis that most commonly affects men. It is caused by high uric acid production which can lead to crystal formation that becomes embedded in the joints. The crystals that are formed can lead to sudden burning pain, stiffness, and swelling in a joint, usually the big toe. As these attacks occur more often, tendons, joints and other tissues may become damaged.
What are the symptoms?
Acute gout attacks are characterized by a rapid onset of pain in the affected joint followed by warmth, swelling, reddish discoloration, and tenderness. Tenderness can be intense so that even a blanket touching the skin over the affected joint can be unbearable. Patients can also develop fever with the acute gout attacks. These painful attacks usually last between a few hours to days, with or without medication. In rare instances, an attack can last for weeks.
What are some risk factors for gout?
Excessive drinking (more than 2 drinks per day for men or more that 1 drink a day for women) and family history increases the risk for gout. Certain medical conditions such as high blood pressure, high cholesterol, and diabetes can increase the risk for gout. Elevated uric acid may occur if taking hydrochlorothiazide, low dose aspirin, niacin, cyclosporine, and pyrazinamide.
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What are some lifestyle changes I can make to prevent gout?
Some lifestyle changes that can help reduce the severity of gout include avoiding alcoholic beverages or drinking in moderation. Alcohol increases the risk of developing high uric acid levels because it interferes with its removal. Drinking water will help the body rid itself of uric acid. As always, maintaining a healthy weight reduces the stress on joints and tendons, therefore, decreasing the risk of elevated uric acid and possible gouty attack. Uric acid is a breakdown product of purines that are part of many foods we eat. Therefore, purine rich foods such as shellfish and meats such as liver, brains, and kidneys should be avoided.
What is this new drug?
Uloric (febuxostat) is the first drug for gout approved in 40 years! It is
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taken once daily and blocks xanthine oxidase (an enzyme) which helps prevent uric acid production. The most commonly reported adverse effects are liver abnormalities, nausea, joint pain, and rash. It should not be taken with other medications that inhibit xanthine oxidase such as theophylline, azathioprine, and mercaptopurine. Other medications used to treat gout include ibuprofen, corticosteroids, and colchicine. Allopurinol is a medication that works similar to Uloric that prevents the onset of gout.
For more information visit www.uloric.com and for additional questions please talk to your pharmacist or physician.
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